Skip to content
All Skills

LangChain - Build LLM Applications with Agents & RAG

Framework for building LLM-powered applications with agents, chains, and RAG. Supports multiple providers (OpenAI, Anthropic, Google), 500+ integrations, ReAct agents, tool calling, memory management, and vector store retrieval. Use for building chatbots, question-answering systems, autonomous agents, or RAG applications. Best for rapid prototyping and production deployments.

Data, AI & Research|v1|Updated 5/18/2026|GitHub source
MCP get_skill({ skillId: "langchain-build-llm-applications-with-agents-rag-f5f9bafa" })

Use this skill with your agent

Create a free account and connect via MCP

Get Started Free
# LangChain - Build LLM Applications with Agents & RAG

The most popular framework for building LLM-powered applications.

## When to use LangChain

**Use LangChain when:**
- Building agents with tool calling and reasoning (ReAct pattern)
- Implementing RAG (retrieval-augmented generation) pipelines
- Need to swap LLM providers easily (OpenAI, Anthropic, Google)
- Creating chatbots with conversation memory
- Rapid prototyping of LLM applications
- Production deployments with LangSmith observability

**Metrics**:
- **119,000+ GitHub stars**
- **272,000+ repositories** use LangChain
- **500+ integrations** (models, vector stores, tools)
- **3,800+ contributors**

**Use alternatives instead**:
- **LlamaIndex**: RAG-focused, better for document Q&A
- **LangGraph**: Complex stateful workflows, more control
- **Haystack**: Production search pipelines
- **Semantic Kernel**: Microsoft ecosystem

## Quick start

### Installation

```bash
# Core library (Python 3.10+)
pip install -U langchain

# With OpenAI
pip install langchain-openai

# With Anthropic
pip install langchain-anthropic

# Common extras
pip install langchain-community  # 500+ integrations
pip install langchain-chroma     # Vector store
```

### Basic LLM usage

```python
from langchain_anthropic import ChatAnthropic

# Initialize model
llm = ChatAnthropic(model="claude-sonnet-4-5-20250929")

# Simple completion
response = llm.invoke("Explain quantum computing in 2 sentences")
print(response.content)
```

### Create an agent (ReAct pattern)

```python
from langchain.agents import create_agent
from langchain_anthropic import ChatAnthropic

# Define tools
def get_weather(city: str) -> str:
    """Get current weather for a city."""
    return f"It's sunny in {city}, 72°F"

def search_web(query: str) -> str:
    """Search the web for information."""
    return f"Search results for: {query}"

# Create agent (<10 lines!)
agent = create_agent(
    model=ChatAnthropic(model="claude-sonnet-4-5-20250929"),
    tools=[get_weather, search_web],
    system_prompt="You are a helpful assistant. Use tools when needed."
)

# Run agent
result = agent.invoke({"messages": [{"role": "user", "content": "What's the weather in Paris?"}]})
print(result["messages"][-1].content)
```

## Core concepts

### 1. Models - LLM abstraction

```python
from langchain_openai import ChatOpenAI
from langchain_anthropic import ChatAnthropic
from langchain_google_genai import ChatGoogleGenerativeAI

# Swap providers easily
llm = ChatOpenAI(model="gpt-4o")
llm = ChatAnthropic(model="claude-sonnet-4-5-20250929")
llm = ChatGoogleGenerativeAI(model="gemini-2.0-flash-exp")

# Streaming
for chunk in llm.stream("Write a poem"):
    print(chunk.content, end="", flush=True)
```

### 2. Chains - Sequential operations

```python
from langchain.chains import LLMChain
from langchain.prompts import PromptTemplate

# Define prompt template
prompt = PromptTemplate(
    input_variables=["topic"],
    template="Write a 3-sentence summary about {topic}"
)

# Create chain
chain = LLMChain(llm=llm, prompt=prompt)

# Run chain
result = chain.run(topic="machine learning")
```

### 3. Agents - Tool-using reasoning

**ReAct (Reasoning + Acting) pattern:**

```python
from langchain.agents import create_tool_calling_agent, AgentExecutor
from langchain.tools import Tool

# Define custom tool
calculator = Tool(
    name="Calculator",
    func=lambda x: eval(x),
    description="Useful for math calculations. Input: valid Python expression."
)

# Create agent with tools
agent = create_tool_calling_agent(
    llm=llm,
    tools=[calculator, search_web],
    prompt="Answer questions using available tools"
)

# Create executor
agent_executor = AgentExecutor(agent=agent, tools=[calculator], verbose=True)

# Run with reasoning
result = agent_executor.invoke({"input": "What is 25 * 17 + 142?"})
```

### 4. Memory - Conversation history

```python
from langchain.memory import ConversationBufferMemory
from langchain.chains import ConversationChain

# Add memory to track conversation
memory = ConversationBufferMemory()

conversation = ConversationChain(
    llm=llm,
    memory=memory,
    verbose=True
)

# Multi-turn conversation
conversation.predict(input="Hi, I'm Alice")
conversation.predict(input="What's my name?")  # Remembers "Alice"
```

## RAG (Retrieval-Augmented Generation)

### Basic RAG pipeline

```python
from langchain_community.document_loaders import WebBaseLoader
from langchain.text_splitter import RecursiveCharacterTextSplitter
from langchain_openai import OpenAIEmbeddings
from langchain_chroma import Chroma
from langchain.chains import RetrievalQA

# 1. Load documents
loader = WebBaseLoader("https://docs.python.org/3/tutorial/")
docs = loader.load()

# 2. Split into chunks
text_splitter = RecursiveCharacterTextSplitter(
    chunk_size=1000,
    chunk_overlap=200
)
splits = text_splitter.split_documents(docs)

# 3. Create embeddings and vector store
vectorstore = Chroma.from_documents(
    documents=splits,
    embedding=OpenAIEmbeddings()
)

# 4. Create retriever
retriever = vectorstore.as_retriever(search_kwargs={"k": 4})

# 5. Create QA chain
qa_chain = RetrievalQA.from_chain_type(
    llm=llm,
    retriever=retriever,
    return_source_documents=True
)

# 6. Query
result = qa_chain({"query": "What are Python decorators?"})
print(result["result"])
print(f"Sources: {result['source_documents']}")
```

### Conversational RAG with memory

```python
from langchain.chains import ConversationalRetrievalChain

# RAG with conversation memory
qa = ConversationalRetrievalChain.from_llm(
    llm=llm,
    retriever=retriever,
    memory=ConversationBufferMemory(
        memory_key="chat_history",
        return_messages=True
    )
)

# Multi-turn RAG
qa({"question": "What is Python used for?"})
qa({"question": "Can you elaborate on web development?"})  # Remembers context
```

## Advanced agent patterns

### Structured output

```python
from langchain_core.pydantic_v1 import BaseModel, Field

# Define schema
class WeatherReport(BaseModel):
    city: str = Field(description="City name")
    temperature: float = Field(description="Temperature in Fahrenheit")
    condition: str = Field(description="Weather condition")

# Get structured response
structured_llm = llm.with_structured_output(WeatherReport)
result = structured_llm.invoke("What's the weather in SF? It's 65F and sunny")
print(result.city, result.temperature, result.condition)
```

### Parallel tool execution

```python
from langchain.agents import create_tool_calling_agent

# Agent automatically parallelizes independent tool calls
agent = create_tool_calling_agent(
    llm=llm,
    tools=[get_weather, search_web, calculator]
)

# This will call get_weather("Paris") and get_weather("London") in parallel
result = agent.invoke({
    "messages": [{"role": "user", "content": "Compare weather in Paris and London"}]
})
```

### Streaming agent execution

```python
# Stream agent steps
for step in agent_executor.stream({"input": "Research AI trends"}):
    if "actions" in step:
        print(f"Tool: {step['actions'][0].tool}")
    if "output" in step:
        print(f"Output: {step['output']}")
```

## Common patterns

### Multi-document QA

```python
from langchain.chains.qa_with_sources import load_qa_with_sources_chain

# Load multiple documents
docs = [
    loader.load("https://docs.python.org"),
    loader.load("https://docs.numpy.org")
]

# QA with source citations
chain = load_qa_with_sources_chain(llm, chain_type="stuff")
result = chain({"input_documents": docs, "question": "How to use numpy arrays?"})
print(result["output_text"])  # Includes source citations
```

### Custom tools with error handling

```python
from langchain.tools import tool

@tool
def risky_operation(query: str) -> str:
    """Perform a risky operation that might fail."""
    try:
        # Your operation here
        result = perform_operation(query)
        return f"Success: {result}"
    except Exception as e:
        return f"Error: {str(e)}"

# Agent handles errors gracefully
agent = create_agent(model=llm, tools=[risky_operation])
```

### LangSmith observability

```python
import os

# Enable tracing
os.environ["LANGCHAIN_TRACING_V2"] = "true"
os.environ["LANGCHAIN_API_KEY"] = "your-api-key"
os.environ["LANGCHAIN_PROJECT"] = "my-project"

# All chains/agents automatically traced
agent = create_agent(model=llm, tools=[calculator])
result = agent.invoke({"input": "Calculate 123 * 456"})

# View traces at smith.langchain.com
```

## Vector stores

### Chroma (local)

```python
from langchain_chroma import Chroma

vectorstore = Chroma.from_documents(
    documents=docs,
    embedding=OpenAIEmbeddings(),
    persist_directory="./chroma_db"
)
```

### Pinecone (cloud)

```python
from langchain_pinecone import PineconeVectorStore

vectorstore = PineconeVectorStore.from_documents(
    documents=docs,
    embedding=OpenAIEmbeddings(),
    index_name="my-index"
)
```

### FAISS (similarity search)

```python
from langchain_community.vectorstores import FAISS

vectorstore = FAISS.from_documents(docs, OpenAIEmbeddings())
vectorstore.save_local("faiss_index")

# Load later
vectorstore = FAISS.load_local("faiss_index", OpenAIEmbeddings())
```

## Document loaders

```python
# Web pages
from langchain_community.document_loaders import WebBaseLoader
loader = WebBaseLoader("https://example.com")

# PDFs
from langchain_community.document_loaders import PyPDFLoader
loader = PyPDFLoader("paper.pdf")

# GitHub
from langchain_community.document_loaders import GithubFileLoader
loader = GithubFileLoader(repo="user/repo", file_filter=lambda x: x.endswith(".py"))

# CSV
from langchain_community.document_loaders import CSVLoader
loader = CSVLoader("data.csv")
```

## Text splitters

```python
# Recursive (recommended for general text)
from langchain.text_splitter import RecursiveCharacterTextSplitter
splitter = RecursiveCharacterTextSplitter(
    chunk_size=1000,
    chunk_overlap=200,
    separators=["\n\n", "\n", " ", ""]
)

# Code-aware
from langchain.text_splitter import PythonCodeTextSplitter
splitter = PythonCodeTextSplitter(chunk_size=500)

# Semantic (by meaning)
from langchain_experimental.text_splitter import SemanticChunker
splitter = SemanticChunker(OpenAIEmbeddings())
```

## Best practices

1. **Start simple** - Use `create_agent()` for most cases
2. **Enable streaming** - Better UX for long responses
3. **Add error handling** - Tools can fail, handle gracefully
4. **Use LangSmith** - Essential for debugging agents
5. **Optimize chunk size** - 500-1000 chars for RAG
6. **Version prompts** - Track changes in production
7. **Cache embeddings** - Expensive, cache when possible
8. **Monitor costs** - Track token usage with LangSmith

## Performance benchmarks

| Operation | Latency | Notes |
|-----------|---------|-------|
| Simple LLM call | ~1-2s | Depends on provider |
| Agent with 1 tool | ~3-5s | ReAct reasoning overhead |
| RAG retrieval | ~0.5-1s | Vector search + LLM |
| Embedding 1000 docs | ~10-30s | Depends on model |

## LangChain vs LangGraph

| Feature | LangChain | LangGraph |
|---------|-----------|-----------|
| **Best for** | Quick agents, RAG | Complex workflows |
| **Abstraction level** | High | Low |
| **Code to start** | <10 lines | ~30 lines |
| **Control** | Simple | Full control |
| **Stateful workflows** | Limited | Native |
| **Cyclic graphs** | No | Yes |
| **Human-in-loop** | Basic | Advanced |

**Use LangGraph when:**
- Need stateful workflows with cycles
- Require fine-grained control
- Building multi-agent systems
- Production apps with complex logic

## References

- **[Agents Guide](references/agents.md)** - ReAct, tool calling, streaming
- **[RAG Guide](references/rag.md)** - Document loaders, retrievers, QA chains
- **[Integration Guide](references/integration.md)** - Vector stores, LangSmith, deployment

## Resources

- **GitHub**: https://github.com/langchain-ai/langchain ⭐ 119,000+
- **Docs**: https://docs.langchain.com
- **API Reference**: https://reference.langchain.com/python
- **LangSmith**: https://smith.langchain.com (observability)
- **Version**: 0.3+ (stable)
- **License**: MIT
#github#broad-capability#external#license-mit#orchestra-research-ai-research-skills#ai-research#machine-learning#mlops#rag#evaluation#paper-writing#aigithubpythonpipopenai-apianthropic-apigemini-api

Related Skills

More skills in Data, AI & Research

Ablation Planner

Use when main results pass result-to-claim (`claim_supported = yes` or `partial`) and ablation studies are needed for paper submission. A secondary Codex agent designs ablations from a reviewer's perspective; the local executor reviews feasibility and implements.

#broad-capability#wanshuiyin-arisMIT

Ablation Planner

Use when main results pass result-to-claim (claim_supported=yes or partial) and ablation studies are needed for paper submission.

#broad-capability#wanshuiyin-arisMIT

About

Provides information about the bitwize-music plugin, its version, and its creator. Use when the user asks about the plugin, its purpose, version, or capabilities.

#github#broad-capabilityCC0-1.0

Ab Test Analysis

Analyze A/B test results with statistical significance, sample size validation, confidence intervals, and ship/extend/stop recommendations. Use when evaluating experiment results, checking if a test reached significance, interpreting split test data, or deciding whether to ship a variant.

#work-life#productivityMIT

Academic Search

Search and analyze academic literature. Find papers, understand research methodologies, and synthesize academic findings for research projects.

#work-life#officeMIT

Adaptyv

How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.

#broad-capability#scienceMIT